The Molecular Profiling Facility provides full service whole genome and targeted molecular profiling of DNA and RNA on multiple platforms. The Facility offers a range of cost and performance options suitable for a variety of experimental projects. While the Facility staff performs most of the assays, investigator-performed studies are actively encouraged through the sharing of Facility procedures, individualized training of investigators or their technical staff, and use of core equipment.

The Core supports quantitative RNA profiling on Affymetrix GeneChips and high-throughput Gene Titan instruments; Luminex FlexMap 3D; Fluidigm BioMark HD; ABI QS 12K real-time PCR machine.

DNA profiling is offered on Affymetrix SNP GeneChip and high-throughput Gene Titan instruments; Fluidigm BioMark HD; ABI QS 12K.

Agilent aCGH platform provides genome-wide chromosomal analysis.

The users benefit from consultation and training available throughout their projects, including during experimental design and budget development, grant preparation, sample accrual, data management and analyses, and manuscript preparation.

For further information, please contact:

Director: Tapan Ganguly, Ph.D. (215-573-7238)

Technical Director: John Tobias, Ph.D. (215-573-4791) for bioinformatics & experimental design

Hetty Rodriguez, M.S. (215-573-6316) for genotyping & gene expression



57 and 68 John Morgan Building
University of Pennsylvania
3620 Hamilton Walk
Philadelphia, PA 19104

Phone: 215-573-6316
Fax: 215-573-4452